Furthermore, a retrospective study with HCV-infected patients before and after antiviral treatment revealed that higher levels of serum LPS and intestinal fatty acid binding proteins, markers of intestinal permeability, were observed in patients with fibrosis/cirrhosis than those of patients without fibrosis and healthy volunteers [149] in both HBV [162–165] and HCV infections [166–168]. This evidence concerns the gene GOT2 and fibrosis.