STOML2 and neoplasm: We therefore extended our STOML2 quantification experiment to a cohort of 119 archived paraffin-embedded specimens of CRC, and the level of STOML2 expression closely associated with CRC clinical staging (p < 0.001), TNM classification (p = 0.003,  p 0.001, and p = 0.048, respectively), and histological differentiation (p = 0.016) but did not correlate with gender, age and tumor localization (Table 1).