In lung cancer, mutations in the chromatin remodeling complex SWI/SNF, such as the genes SWI/SNF Related, matrix associated actin dependent regulator of chromatin, subfamily A, member 4 (SMARCA4) and AT‐rich interactive domain‐containing protein 1A (ARID1A), sensitize cells to OXPHOS metabolism. Here, ARID1A is linked to lung cancer.