In cohort B, 13 (13/15, 86.7%) patients experienced TRAE, with the most common TRAEs being alanine aminotransferase increased (n = 7, 46.7%), hypoalbuminemia (n = 6, 40.0%), anemia (n = 5, 33.3%), and platelet count decreased (n = 5, 33.3%). The gene discussed is GPT; the disease is Hypoalbuminemia.