TP53 and non-small cell lung carcinoma: Clearly, there was an agent-dependent decrease in cell proliferation following the treatment of both the TP53 MUT and WT NSCLC and CRC cells, with the decrease in cell growth following 5 μmol/L treatment compared the growth of the untreated cells being significant at days 3–4 for the A549, days 2–4 for H23 and days 3–4 for H29.