A recent review article confirmed the relationship between rs3842570, rs3792267, rs2975760, and rs5030952 SNPs of the CALP10 gene and PCOS via the insulin resistance gene, which was confirmed as a risk factor, and these SNPs have been proven as possible causes for various phenotypes in PCOS women, affecting androgen production and causing hypercholesterolemia. This evidence concerns the gene INS and Hypercholesterolemia.