These 12 DRLs are closely associated with GYS1, NDUFS1, NDUFA11, OXSM, LRPPRC, NUBPL, NCKAP1, RPN1, SLC3A2, and SLC7A11 (Supplementary Figure 1A), which are intimately correlated to a poorer prognosis of CRC except for SNHG16 (Supplementary Figure 1B). The gene discussed is NDUFS1; the disease is colorectal carcinoma.