KEGG-based enrichment analysis revealed several pathways significantly enriched among the differentially expressed genes, including those associated with NOD-like receptor signalling pathway, apoptosis, TNF signalling pathway, NF-κB signalling pathway, necroptosis, lipid and atherosclerosis, influenza A, Kaposi sarcoma-associated herpesvirus infection, C-type lectin receptor signalling pathway, and RIG-I-like receptor signalling pathway (Fig. 5D). Here, CLEC4D is linked to Herpesviridae infectious disease.