Many studies on the antitumor potential of FLT3/FLT3LG have shown that FLT3LG, as a single agent, could delay or reverse the growth of methyl choline-induced fibrosarcoma27, C3L5 breast tumors28, B16 melanoma and EL4 thymoma (THYM) 29. This evidence concerns the gene FLT3LG and melanoma.