Ginsenoside 20(S)-Rh2 effectively inhibited IL-6 induced signaling pathway activation (such as signal transducer and activator of transcription 3, STAT3), and IL-6 induced gene expression of matrix metalloproteinases (such as MMP-1, MMP -2, and MMP -9), resulting in inhibition of cancer cell invasion 55. Here, STAT3 is linked to cancer.