mRNA levels of PCa+Docetaxel, PCa+LDH-A inhibitor, and PCa+LDH-A inhibitor + Docetaxel groups were found to be statistically lower compared to the PCa group (p < 0.0001, p < 0.001 and p < 0.0001 respectively) (Figure 5 B). This evidence concerns the gene LDHA and posterior cortical atrophy.