The liver-type OATP1B3 (lt-OATP1B3) is an androgen transporter, and polymorphic variations in the SLCO1B3 gene are associated with poor overall survival from diagnosis, poor progression-free survival on androgen deprivation therapy biochemical recurrence and prostate cancer-specific mortality 25-29. This evidence concerns the gene SLCO1B3 and Familial prostate cancer.