CDCA5 and cancer: After eliminating tumors with insufficient sample size (Figure S1D), significantly reduced methylation levels of the CDCA5 promoter were seen in 13 kinds of cancer, including BLCA, BRCA, COAD, HNSC, KIRC, KIRP, LIHC, LUAD, LUSC, PRAD, TGCT, THCA, and UCEC (Figure 4A; P<0.001).