ASMT and major depressive disorder: Put together, these findings reflect the fact that ASMT geneencoding the melatonin synthesis enzyme acetylserotoninO-methyltransferase is one of the key hormones involved inthe regulation of molecular and genetic processes in all humanbody in general including aggression (Melke et al., 2008; Trent et al., 2013; Gaitanis et al., 2023; Kang et al., 2023),depression (Talarowska et al., 2014), ontogenesis (LiW.