Since we evaluated how strictinin affected ROR1-mediated AKT-GSK3β signaling in PC3 cells, we also wanted to determine the impact of strictinin on ROR1 and AKT-GSK3β signaling in DU145, which is another ARneg-AI, ROR1 expressing prostate cancer cell line [30]. Here, AKT1 is linked to Familial prostate cancer.