GPX4 and acute kidney injury: In rats with sepsis-induced acute kidney injury (SI-AKI) and human renal tubular epithelial cells (HK-2) with LPS-induced ferroptosis, ginsenoside Rg1 can reduce lipid peroxidation and ferroptosis by reducing iron content, FTL, FTH, and MDA levels while increasing GPX4, FSP1, and GSH levels.