To further confirm the role of β‐catenin in CXCR4‐induced renal fibrosis, we pretreated HK‐2 cells with ICG‐001, a small molecule inhibiting β‐catenin‐mediated gene transcription,41 and then transfected cells with pFlag‐CXCR4 plasmid. Here, CXCR4 is linked to renal fibrosis.