PDLIM7 and nasopharyngeal carcinoma: Taking EBV in NPC as an example, the LMP1 protein from EBV genome can interfere with the activity of DNMTs enzyme, leading to the methylation modification of the promoter regions of genes such as E-cadherin [9], RAR-β2 [10], RASSF1A [11, 12] and CDKN2A [11, 12], thereby affecting their expression.