Through EBV methylation capture sequencing on nasopharyngeal brushing samples from NPC and nasal NKTCL patients (Fig. 3B–C; Fig. 4A), we found that most of the CpG sites in these two group samples were hyper-methylated; while, a small portion of hypo-methylated genes included LMP1, LMP2A, BNLF2a and BNLF2b, which was consistent with other tumor samples. The gene discussed is PDLIM7; the disease is neoplasm.