Moreover, these engineered microglia promoted an anti-tumour microenvironment by increasing CD86 antigen presentation costimulatory molecule and TNF-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\alpha$$\end{document}α, a pro-inflammatory cytokine, and decreasing immunosuppressive regulatory T lymphocytes [37]. This evidence concerns the gene TNF and neoplasm.