It is crucial for chromosome segregation and cytokinesis to be regulated by the chromosomal passenger complex (CPC), including Aurora B kinase, INCENP, Survivin and Borealin. Tuncel et al., study have shown that between Aurora B and Survivin expression has been verified to correlated with pathological features in colorectal carcinoma using immunohistochemistry [58]. Here, BIRC5 is linked to colorectal carcinoma.