Categories with acute megakaryoblastic leukemia (AMKL) or acute erythroid leukemia (AEL) phenotypes are clearly enriched in infants, whereas CBF leukemias and mutation-defined leukemias (for example, UBTF, NPM1, CEBPA) were enriched in adolescents and young adults (Fig. 4a and Extended Data Fig. 4b). This evidence concerns the gene CEBPA and acute erythroid leukemia.