Notably, among KMT2A fusion partners, MLLT3 and MLLT10 were found in both monocytic AML and AMKL; however, these fusions preferentially show AMKL phenotypes in infants, suggesting that AMKL phenotypes are defined both by driver alterations and by developmental stages as discussed previously43,44. Here, MLLT10 is linked to acute myeloid leukemia.