NPM1 and leukemia: Categories with acute megakaryoblastic leukemia (AMKL) or acute erythroid leukemia (AEL) phenotypes are clearly enriched in infants, whereas CBF leukemias and mutation-defined leukemias (for example, UBTF, NPM1, CEBPA) were enriched in adolescents and young adults (Fig. 4a and Extended Data Fig. 4b).