Intriguingly, multiple ribosomal protein subunits were also among the GBM diagnostic proteins (RPS2, RPL18, RPL28, RPL7, RPL6, RPS8, RPL7A, RPL10, RPL13A), all of which were significantly higher in GBM uEVs relative to HC (Fig. 2b). This evidence concerns the gene RPS8 and glioblastoma.