Compared to allergic rhinitis mice, CCR3mAb2 and CCR3mAb3 groups had increased trends in Th1 cytokines (IL-2 and IFN-γ), with statistical significance; and decreased trends in Th2 cytokines (IL-4, IL-5, and IL-13) (Fig. 9). Here, IL4 is linked to allergic rhinitis.