The major findings of this study are as follows: 1) according to the analyses using the quintiles of mean BT during the first seven days after acute ischemic stroke, higher BT was significantly associated with poor acute neurological outcomes (assessed by neurological improvement or worsening) and poor functional outcomes at three months, even after adjusting for confounders including neurological severity, C-reactive protein levels, and post-stroke acute infections. Here, CRP is linked to Stroke.