ADGRE1 and obesity due to melanocortin 4 receptor deficiency: Flow cytometry showed significantly higher levels of CCR3 on EOS from lean patients (BMI < 25 kg/m2) compared with EOS isolated from people with obesity (BMI ≥ 30 kg/m2) (EGF-like module-containing mucin-like hormone receptor-like 1 [EMR1], 2,074,903 ± 151,214 molecules of equivalent soluble fluorochrome [MESF] units versus 1,610,418 ± 142,751 MESF units, respectively, P = 0.02; Figure 5B).