HIF1A and atherosclerosis: By regulating signaling pathways such as those related to lipid and atherosclerosis pathway, HIF-1 signaling pathway, chemokine signaling pathway, leukocyte migration through endothelia, antigen processing and presentation, CSJD may play an important role in inhibiting dengue virus replication, enhancing anti-inflammatory responses, improving immunity, regulating coagulation and fibrinolysis, and modulating energy and lipid metabolism.