ALB and diabetic kidney disease: It has been found that the course of DKD is positively correlated with inflammatory mediators in plasma[54,55] and closely related to the excretion of urinary albumin.[56,57] Activation of numerous transcription factors and kinases promotes the production of pro-inflammatory trend factors, cytokines, and adhesion factors, and accumulate in the renal tissue, thereby inducing renal injury.[58] Meta-analysis showed that 24-hour UTP, ALB, and β2-MG were significantly different.