CRP and diabetic kidney disease: It has been found that SIN can reduce the renal inflammatory response and delay renal cell sclerosis and interstitial fibrosis by down-regulating inflammatory factors, inhibiting immune-mediated inflammatory responses, and reducing AGEs.[48] This study included 7 articles, 5 of which assessed the clinical effectiveness of SIN in treating DKD, 6 articles evaluated the efficacy of proteinuria from 24-hour UTP, and 2 articles evaluated CRP, with statistical differences in all indicators.