In total, 16 (CD274, CTLA4, BTLA, CD244, CD96, CSF1R, HAVCR2, IL10, KIR2DL1, KIR2DL3, LAG3, PDCD1, PDCD1LG2, TGFB1, TGFBR1, and TIGIT) and four (IL10RB, KDR, LGALS9, and VTCN1) were significantly up-regulated and down-regulated in CSCC versus ADC, respectively. This evidence concerns the gene CD274 and AIDS dementia complex.