Abnormal phosphorylation and accumulation of the microtubule‐associated protein tau occurs with age and disease; whereas some diseases including Alzheimer's have enriched pathological tau largely in neurons, other diseases like progressive supranuclear palsy, corticobasal degeneration, and TBI show pathological tau accumulation in both neurons and glia (Berry et al., 2001; Schmidt et al., 2001; Tagge et al., 2018). The gene discussed is MAPT; the disease is progressive supranuclear palsy.