PDCD1 and myocarditis: Recognizing that multiorgan involvement has been reported in cases of ICI-induced myocarditis,24 we also performed a histopathological examination of the lungs, kidney, skeletal muscle, and liver in ISOprimed/ISOinjury female PD-1−/− mice at baseline and on days 7, 14, and 35 after high-dose ISO injection.