A combined PRS of CHD biomarkers (BioPRS) was derived across PRS of 10 biomarkers (Supplemental Table 1) (HDL, LDL, TRIG, total cholesterol, systolic blood pressure, CPD, HbA1c, CRP, creatinine, ApoB, ApoA1) by combining the individual biomarker PRS generated with PRS-CS on 1,106,191 SNPs. Here, APOA1 is linked to coronary artery disorder.