In an RNA-seq analysis of oral mucosal ulcers and diabetic foot ulcer tissues, one investigator found that keratins associated with trauma activation (KRT6, KRT16, and KRT17) and keratins associated with cell differentiation (KRT1, KRT2, and KRT10) were upregulated in oral mucosal ulcer tissues to promote ulcer wound repair. This evidence concerns the gene KRT2 and ulcer disease.