Moreover, correlative analysis revealed that the increased abundance of Haemophilus, Porphyromonas, Prevotella, and Capnocytophaga was associated with a greater AD pathology measured by CSF p-tau/Aβ1–42 ratio, whereas the higher abundance of Rothia, Olsenella, and Actinomyces found in healthy controls were associated with less AD pathology. The gene discussed is MAPT; the disease is Alzheimer disease.