In addition, miR-29b was also found to alleviate the inflammatory response after ischemic stroke through tumor necrosis factor (C1QTNF) 6 [40] While targeting the miR-29b/C1QTNF6 axis in cerebral ischemic injury promotes leukocyte inflammation [41], miR-29b could also reduce alcohol-induced inflammation by targeting the signal transducer and activator of transcription 3 (STAT3) [42]. This evidence concerns the gene STAT3 and ischemic stroke.