The EVs were sorted into an exosome‐dominated subpopulation (Exo) using a 1/1/1 by weight mixture of CD63/CD81/CD9 antibodies, a microvesicle‐dominated subpopulation (MV) using a 1/1 by weight mixture of ARF6/Annexin A1 (ANXA1) antibodies,[37, 38] and a PDAC tumor‐associated EV subpopulation (tEV) using a 1/1/1 by weight mixture of EGFR/EpCAM/GPC1 antibodies (Figure2A). This evidence concerns the gene CD81 and neoplasm.