It is recognized that elevated GPC1 expression is associated with an unfavorable prognosis in PDAC.[50] Additionally, the expression of GPC1 protein on PDAC cell lines influences their resistance to chemotherapeutic drugs.[51, 52, 53] To ascertain the levels of the GPC1 membrane protein expression in pancreatic cancer cells, we conducted flow cytometry (Figure 7A). Here, GPC1 is linked to familial pancreatic carcinoma.