However, not all clinical manifestations are included in the criteria for APS, nor are antiphospholipid antibodies, which are divided into criteria (lupus anticoagulant (LA), anticardiolipin (ACL), anti-β2-glycoprotein I (anti-β2GPI)) and non-criteria (antiannexin A2, antivimentin/cardiolipin complex, antiannexin A5, antiphosphatidylethanolamine, antiphosphatidylinositol, etc.). The gene discussed is APOH; the disease is autoimmune polyendocrinopathy.