FOLH1 and neoplasm: Despite the promising in vitro apoptosis induction capability, the considerable activity of 223RaA-silane-PEG and 223RaA-silane-PEG-D2B in off-target organs such as the liver, lungs, spleen, and the bones of PSMA-positive LNCaP C4-2 tumor bearing mice may hamper the application of these derivatives in imaging settings.