We adjusted for important clinical factors, and the adjusted OR of CTSB is presented in Figure 5B. After we adjusted for the baseline FVC, we found that CTSB was significantly associated with progressive IPF (adjusted OR = 2.61, 95% CI 1.94–3.51, p < 0.001, Figure 5B). Here, CTSB is linked to idiopathic pulmonary fibrosis.