Snhg6 expression was induced in a high-fat/high-cholesterol (HF/HC) and diethylnitrosamine (DEN) model of mouse NAFLD/HCC; adeno-associated virus (AAV8)-mediated delivery of SNHG6 accelerated the process, and AAV8 delivering shRNA for SNHG6 reversed the process [158]. This evidence concerns the gene SNHG6 and hepatocellular carcinoma.