A search for RNA-binding proteins (RBPs) regulating HCC identified that RBP CCT3 regulated lipid metabolism in HCC cells by regulating the lncRNA LINC00326, and interference with CCT3/LINC00326 interaction inhibited the growth of HuH-7 tumors implanted in zebrafish [164]. The gene discussed is CCT3; the disease is hepatocellular carcinoma.