AXIN1 and cancer: Recently, small-molecular AXIN stabilizers have been synthesized (e.g., KYA1797K), whose anti-cancer properties were demonstrated [101] in transgenic mice (C57BL/6J-ApcMin/+, B6.129S-Krastm3Tyj, C57BL/6J-Apc1638N) as well as xenograft model.