In addition, there are combination pharmacotherapies that can treat AF, such as drugs prescribed for diabetes mellitus (DM) and other disorders, including dipeptidyl peptidase-4 inhibitors, selective sodium-glucose cotransporter inhibitors 2, ubiquinone, metformin, thiazolidinediones, fibrates, trimetazidine, and ranolazine [4]. This evidence concerns the gene DPP4 and diabetes mellitus.