MAPT and Parkinson disease: Four large autopsy studies of PD showed consistent results: while co-morbid ADNC was present in 19–31.5% of total PD cases, the rate of co-morbid ADNC in PDD ranged from 21.5% to 89.4% [405,413,415], tau pathology being more severe in the prefrontal than in the temporal cortex [416].