OVA-induced asthma associated with obesity resulted into an increase in iNOS-expressing macrophages and neutrophils, increased levels of IL-4, IL-9, IL-17A, leptin and IFN-γ in the lung, higher goblet cell hyperplasia, and elevated mast cell influx into the lung and trachea [111]. Here, IL17A is linked to obesity due to melanocortin 4 receptor deficiency.