To confirm that TLR2 stimulates NK cells, Ke et al. demonstrated that treatment with Strongylocentrotus nudus egg polysaccharide, a TLR2 agonist, induces NK cell proliferation, cytotoxicity and release of interleukin (IL)-2 and IFN-γ in a mouse model of lung cancer [22]. This evidence concerns the gene TLR2 and lung cancer.