Bacterial vaginosis was characterized by reduced IL-18 and GATA3 mRNA expression; anaerobic vaginitis was accompanied by increased IL-1b, IL-10, and TLR4 mRNA levels; increased IL-1b and TLR4 mRNAs were detected in vulvovaginal candidiasis. This evidence concerns the gene TLR4 and vulvovaginal candidiasis.