Studies of familial PD have identified other causative genes implicated in the autosomal dominant form of the disease (e.g., LRRK2—encoding leucine-rich repeat kinase 2 and VPS35—encoding vacuolar protein sorting 35) or autosomal recessive (e.g., PRKN—encoding Parkin RBR E3 Ubiquitin Protein Ligase, PINK1—encoding PTEN-induced kinase 1, ATP13A2—encoding lysosomal type 5 P-type ATPase, PLA2G6—encoding phospholipase A2, and FBX07—encoding F-box protein 7) [24]. This evidence concerns the gene VPS35 and Parkinson disease.