PKHD1L1 and cancer: Figure 1B shows that the PKHD1L1 mRNA expression was downregulated in 14 cancer types, including skin and lung cancer. Increased PKHD1L1 expression was observed only in lymphoid neoplasm diffuse large B cell lymphoma (DLBCL) in the GEPIA. Collectively, the results of this study showed that the mRNA expression of the PKHD1L1 gene in several types of cancer, including SKCM and LUAD, was significantly lower than that in normal tissues.