The observed decrease in granulocytes among mice infected with PRV-ΔTK/ΔgE or PRV-∆TK-(CD2v)-∆gE-(p54) signifies that the double knockout of TK and gE genes effectively eliminates T-cell immunosuppression from granulocytes, thereby enhancing the ability of the immune system against viral infection. Here, TKT is linked to viral infectious disease.