In an observational study it was found that sNGAL (serum neutrophil gelatinase-associated lipocalin) demonstrated lower accuracy as a diagnostic parameter [8] whereas other prospective observational study of 52 patients with COVID-19 carried out by Pode Shakked et al., they found that serum creatinine and serum cystatin C (sCysC) measured at emergency department (ED) admission were highly predictive for AKI and also reliable in predicting the need for hemodialysis [9]. This evidence concerns the gene LCN2 and acute kidney injury.