In one particular study, Pieri M et al., showed that SAA levels in the serum can be very informative for COVID-19 patients admitted to hospital and that SAA might be a good prognostic marker in COVID-19 disease alone and/or in combination with other inflammatory biomarkers such as D-dimer, hsCRP, IL-6 and procalcitonin and can help distinguish the critically ill patient [15]. This evidence concerns the gene IL6 and COVID-19.