Low TET2 expression negatively correlates with the histological classification of BC lesions, activated CD8+ T cells, CD56+ natural killer cells, gamma delta T cells, macrophages, myeloid-derived suppressor cells (MDSC), and monocytes and positively correlates with 5hmC levels, immune-infiltrating tumor-associated fibroblast, and memory B cells [41,43]. This evidence concerns the gene TET2 and neoplasm.