Additionally, Catalase (CAT) reprimes the TET1 expression, inhibiting the TARDBP expression by decreasing hydroxymethylation levels in its promoter in MDA-MB-468, MDA-MB-231, SUM149, and HCC70 BC cells, decreasing the formation of mammospheres and Cancer Stem Cells (CSCs) [32]. This evidence concerns the gene TET1 and breast cancer.